This diagnostic process utilizes laser-based technology to analyze the physical and chemical characteristics of blood, bone marrow, or lymph node cells. A targeted collection of antibodies, each tagged with a unique fluorescent dye, binds to specific proteins on the surface and within these cells. The resulting fluorescent signals are measured and interpreted to identify cell populations, quantify their proportions, and characterize their features, such as size, granularity, and protein expression. This data provides crucial insights into the presence and classification of hematologic malignancies.
Immunophenotyping via this method is invaluable in diagnosing and managing various blood cancers. It allows for precise disease classification, guiding treatment strategies and predicting prognosis. This advanced technique helps distinguish between different types of leukemia and lymphoma, identify specific subtypes, and detect minimal residual disease after treatment. Historically, microscopic examination of cells provided limited information. The development and refinement of this technology represents a significant advancement, enabling clinicians to make more informed decisions based on detailed cellular information.
